You must cite the textbook as a source, including the chapter and page number. B

You must cite the textbook as a source, including the chapter and page number. B

You must cite the textbook as a source, including the chapter and page number. Be as specific as possible in answering the questions. Provide details. Do NOT use a chatbot or internet searches to complete the assignment. Not adhering to instructions could lead to a grade of zero.
A. Suppose that a a large university medical center has hired you to design a case-control study to assess the following hypothesis: daily intake of a baby aspirin (81 mg) protects against migraine headaches.
Be sure that your design addresses the following elements:
1. Refine the study hypothesis to be as specific as possible and contain all elements of a “good” hypothesis.
2. How will you identify and define the cases?
3. Are there any exclusion criteria that you would apply?
4.How will you sample from the underlying population for your “controls”?
5. Who will you select as controls?
6.How will you select them?
7.How will you define the exposure of interest?
8.How will you collect the information on exposure?
9.What other information do you want to know about participants that may be related to the exposure of interest and/or the outcome (potential confounders)? What will you be able to collect, and what will you be unable to collect?
10. Which measures of disease frequency and association will you calculate?
11. What are the strengths and limitations of your study?
12 Which limitations could be removed by using a different study design?
13 What other information would you like to know to design this study?
14. List and describe four sources to identify controls for case-control studies. Discuss the strengths and limitations of each source.

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